Searchable abstracts of presentations at key conferences in endocrinology

ea0087p11 | Poster Presentations | UKINETS2022

Metastatic VIPoma with Severe WDHA Syndrome: Natural History over 20 years documenting histological dedifferentiation - an illustrative case

Saunders Elspeth , Sizer Bruce , Collins Jennifer , Gopalkrishnan Srinivasan , Skelly Robert , Petty Robert , McStay Mary

A 51 year old female patient presented in 2000 with a 7 month history of diarrhoea and weight loss. Bloods revealed hypokalaemia (1.9). Infection and malabsorption screen negative, but patient remained hypokalaemic despite maximum iv and oral replacement. No abnormality was found endoscopically. Fasting gut hormone profile showed raised Vasoactive Intestinal Polypeptide (VIP) >400 (NR <30). CT scan confirmed 5cm mass in body of pancreas, no metastatic disease. Response...